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  1. The myth of cobra venom cytotoxin: More than just direct cytolytic ...

    Jun 1, 2022 · Cytotoxin is abundant in the cobra venom and undeniably plays a major role in causing local necrotic lesions at the wound site upon snakebite. Cytotoxin exhibits differential cytotoxic …

  2. Current Insights in the Mechanisms of Cobra Venom Cytotoxins and …

    Dec 1, 2022 · In some African cobras, they comprise more than 70% of the venom proteome. Being less toxic than cobra venom NTXs, CTXs act non-specifically, thereby affecting various tissues and …

  3. Cobra Cytotoxins: Structural Organization and Antibacterial Activity

    Cardiotoxins (cytotoxins, CT) are β-structured proteins isolated from the venom of cobra. They consist of 59–61 amino acid residues, whose antiparallel chains form three ‘fingers’. In contrast to neurotoxins …

  4. Frontiers | Cytotoxicity of Snake Venoms and Cytotoxins From Two ...

    Nov 11, 2020 · Venoms of cobras (Naja spp.) contain high abundances of cytotoxins, which contribute to tissue necrosis in cobra envenomation. The tissue-necrotizing activity of cobra cytotoxins, …

  5. Cobratoxin - Wikipedia

    The cobras that produce the toxin live in tropical and subtropical regions of Africa and Asia. The venom, produced by these snakes, is a mixture of proteins, carbohydrates, and other substances. The …

  6. Researchers Discover Genes Key to Spitting Cobra Venom's Cytotoxicity

    Jul 25, 2024 · In a recent study published in Science Translational Medicine, scientists used functional genomics to dissect and understand the cytotoxicity of spitting cobra venom and define the genetic …

  7. The myth of cobra venom cytotoxin: More than just direct ... - PubMed

    Apr 4, 2022 · Cobra venom cytotoxin (CTX) is a non-enzymatic three-finger toxin that constitutes 40-60% of cobra venom. Thus, it plays an important role in the pathophysiology of cobra envenomation, …

  8. Cobra venom cytotoxin (CTX) is a non-enzymatic three-finger toxin that constitutes 40–60% of cobra venom. Thus, it plays an important role in the pathophysiology of cobra envenomation, especially in …

  9. Unveiling the functional epitopes of cobra venom cytotoxin by ...

    Jul 28, 2023 · Approximate 70% of cobra venom is composed of cytotoxin (CTX), which is responsible for the dermonecrotic symptoms of cobra envenomation.

  10. Cobra | Venomous Snake Species & Characteristics | Britannica

    Cobra, any of various species of highly venomous snakes, most of which expand the neck ribs to form a hood. Cobras are found from southern Africa through southern Asia to islands of Southeast Asia.