Gene therapy - Mayo Clinic
Apr 23, 2024 · Gene therapy aims to fix a faulty gene or replace it with a healthy gene to try to cure disease or make the body better able to fight disease. It holds promise as a treatment for a wide …
Stem cell therapy for degenerative intervertebral disk disease: Q and A ...
Jun 23, 2017 · In collaboration with orthopedic and neurosurgery researchers, we are examining the epigenetics in identifying gene expression profiles associated with disk degeneration. The purpose of …
Chemotherapy for breast cancer - Mayo Clinic
Jan 10, 2025 · Gene expression profiling tests, such as Oncotype DX, EndoPredict and MammaPrint, may help predict the risk of recurrence and give your doctor an idea of how your cancer cells might …
Novel surgical approach for retinal gene therapy shows promise
Luxturna was approved by the Food and Drug Administration in 2017 for RPE65 -related inherited retinal dystrophy and was the first in vivo gene therapy. While subretinal injection of adeno-associated virus …
TERT expression may better predict meningioma behavior
Oct 7, 2025 · Researchers co-led by a Mayo Clinic Neurosurgery chair have demonstrated that telomerase reverse transcriptase (TERT) gene expression in meningiomas predicts earlier disease …
Genetic testing - Mayo Clinic
Apr 14, 2020 · Genetic testing: Learn why it's done, how to prepare and what to expect from diagnostic tests, carrier tests, prenatal tests and newborn screening.
Phase 1 clinical trial testing gene therapy treatment for knee ...
Oct 10, 2025 · Results demonstrate that injection of local gene therapy for knee joints is safe and achieves sustained, intra-articular concentrations of a therapeutic gene product.
HER2-positive breast cancer: What is it? - Mayo Clinic
Apr 9, 2024 · HER2-positive breast cancer tends to be more aggressive than other types of breast cancer. Treatments that target HER2 are very effective.
Publications - Andrew L. Folpe, M.D. - Mayo Clinic
Malignant melanotic schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of "melanotic schwannoma".
mRNA transfection improves CTL response in immunotherapy
Apr 30, 2022 · Reduced NKG7 expression altered cytolytic granule number, trafficking and calcium release, resulting in decreased killing of tumor cells by CTLs. Transfection of CTLs with NKG7 …