The aminoacylation reaction, which is catalysed by aminoacyl-tRNA synthetases (aaRSs), fuses each amino acid to its cognate tRNA. This reaction requires amino acid activation through condensation of ...

There are different kinds of ribonucleic acids that play essential roles in many aspects of molecular biology, including the creation of proteins from gene sequences in DNA. One type of ribonucleic ...

A new discovery suggests that the number of human genomic loci that might be coding for tRNAs is nearly double what is currently known. Transfer RNAs (tRNAs) are ancient workhorse molecules and part ...

Alltrna is advancing a new class of genetic medicines based on the power of tRNA biology to universally treat Stop Codon Disease, which encompasses thousands of genetic diseases caused by a premature ...