Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein ...

Dewpoint has selected a novel small molecule to prevent the formation of abnormal TDP-43 protein clumps in ALS and other ...

Booster Therapeutics (Germany) focuses on developing small-molecule proteasome activators for neurodegenerative disease using ...

Targeted protein degradation (TPD) is transforming drug discovery by leveraging the cell’s natural protein disposal systems to eliminate disease-causing proteins. Innovators are making rapid and ...

Immunotherapy has transformed the field of cancer medicine. It has extended survival rates, reduced toxicity, and, in some cases, completely eradicated the tumor. Immunotherapy is a form of cancer ...

Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, ...