Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

New modeling shows how synonymous mutations -- those that change the DNA sequence of a gene but not the sequence of the encoded protein -- can still impact protein production and function. New ...

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).

A research team led by Prof. XU Zhiheng from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has identified Tapt1, together with its partner Suco, as important ...

Researchers have developed the first mouse model for a mitochondrial tRNALeu mutation, showing that the associated metabolic disorder results from faulty RNA processing. Studying the role of ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...