A recent randomised controlled trial showed that proton pump inhibitors (PPIs), compared with histamine-2 receptor antagonists (H2RAs), induce greater gut microbiome alterations and oral-to-gut ...

Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems. PPIs are activated in the acid-producing cells of the ...

Proton pump inhibitors (PPIs), widely prescribed for acid-related disorders like GERD and peptic ulcers, are associated with significant adverse effects when used long-term. This review highlights ...

While 50%-80% of PPI prescriptions are unjustified, particularly for unnecessary nonsteroidal anti-inflammatory drug (NSAID)-related ulcer prophylaxis, PPIs remain underprescribed for patients at risk ...

A recent Scientific Reports study investigates whether the association between proton pump inhibitors (PPIs) and the use of histamine-2 receptor antagonists (H2RA) affects the risk of chronic kidney ...

The NHS has important guidance on its website for anyone prescribed lansoprazole, especially if they have been taking it for ...