Squamous cell carcinoma (SqCC) is the second most prevalent type of lung cancer. However, treatment options for these patients remain limited and have remained largely unchanged over decades. Now, a ...

Scientists have shown that changes in the tumor matrix surrounding squamous cell carcinomas differ between patients with better and worse clinical outcomes. Researchers at the Garvan Institute of ...

The matrix metalloproteinase (MMP) family of enzymes is comprised of critically important extracellular matrix remodeling proteases whose activity has been implicated in a number of key normal and ...

Collagen type XII plays a key role in regulating the organization of the tumor matrix, reveals a new study from the Garvan Institute of Medical Research. A team of scientists led by Associate ...

Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen ...

Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen ...

As with weeds in a garden, it is a challenge to fully get rid of cancer cells in the body once they arise. They have a relentless need to continuously expand, even when they are significantly cut back ...