Severe heart attacks often progress to end-stage heart failure because the dearth of heart muscle cells diminishes pumping power of the heart’s left ventricle. The damaged heart, unable to repair ...
University of Alabama at Birmingham researchers, led by Jianyi “Jay” Zhang, M.D., Ph.D., and Lei Ye, M.D., Ph.D., generated the human leukocyte antigen-knockout ...
The induction of the cell cycle in cardiomyocytes involves the activation of specific genes that are responsible for regulating cell division and growth. Our laboratory has discovered several ...
Thought LeadersJohn Yates Professor in the Department of Molecular MedicineScripps Research Institute In this interview conducted at Pittcon 2024, we spoke to Professor John Yates from the Scripps ...
In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that ...
The problem is that mammalian heart muscle cells, known as cardiomyocytes, lose their ability to proliferate shortly after birth. Researchers have long sought to induce these cells to start dividing ...
Injecting infarcted pig hearts with specially bioengineered cells significantly decreased the infarct area and improved heart function, showing possible clinical relevance “It is widely acknowledged ...
In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that ...
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